Rosemary

Latin name

Rosmarinus officinalis L.

Origin

Mediterranean basin

Bibliographical references

Comparative choleretic and hepatoprotective properties of young sprouts and total plant extracts of Rosmarinus officinalis in rats.
Hoefler C, Fleurentin J, Mortier F, Pelt JM, Guillemain J.
J Ethnopharmacol. 1987 Mar-Apr;19(2):133-43.
Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/3613606
Relaxant effect of the volatile oil of Rosmarinus officinalis on tracheal smooth muscle.
Aqel MB
J Ethnopharmacol. 1991 May-Jun;33(1-2):57-62.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/1943174
Spasmolytic activity of Rosmarinus officinalis L. involves calcium channels in the guinea pig ileum.
Ventura-Martínez R, Rivero-Osorno O, Gómez C, González-Trujano ME.
J Ethnopharmacol. 2011 Oct 11;137(3):1528-32.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/21896322
In vitro antibacterial activity of some plant essential oils.
Prabuseenivasan S, Jayakumar M, Ignacimuthu S.
BMC Complement Altern Med. 2006 Nov 30;6:39.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/17134518
Antimicrobial and antioxidant properties of rosemary and sage (Rosmarinus officinalis L. and Salvia officinalis L., Lamiaceae) essential oils.
Bozin B, Mimica-Dukic N, Samojlik I, Jovin E.
J Agric Food Chem. 2007 Sep 19;55(19):7879-85.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/17708648/
Sage and rosemary essential oils versus BHT for the inhibition of lipid oxidative reactions in liver pâté.
Estévez M., Ramírez R., Ventanas S., Cava R.
LWT—Food Science and Technology. 2007;40(1):58–65
ScienceDirect: http://www.sciencedirect.com/science/article/pii/S0023643805001623
Antibacterial activity and anticancer activity of Rosmarinus officinalis L. essential oil compared to that of its main components.
Wang W, Li N, Luo M, Zu Y, Efferth T.
Molecules. 2012 Mar 5;17(3):2704-13.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/22391603/
New insights into antibacterial and antioxidant activities of rosemary essential oils and their main components
Adriana M. Ojeda-Sana, Catalina M. van Baren, Miguel A. Elechosa, Miguel A. Juárez, Silvia Moreno
Food Control Volume 31, Issue 1, May 2013, Pages 189–195
ScienceDirect: http://www.sciencedirect.com/science/article/pii/S0956713512005221
An in vitro evaluation of the antibacterial activity of the non-volatile phenolic fraction from rosemary leaves.
Sacco C, Bellumori M, Santomauro F, Donato R, Capei R, Innocenti M, Mulinacci N.
Nat Prod Res. 2014 Dec 4:1-8.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/25471257
Antioxidative activity of Rosmarinus officinalis L. essential oil compared to its main components.
W. Wang, N. Wu, Y.G. Zu, , Y.J. Fu
Food Chemistry Volume 108, Issue 3, 1 June 2008, Pages 1019–1022
ScienceDirect: http://www.sciencedirect.com/science/article/pii/S0308814607011697
Relationship between the antioxidant capacity and effect of rosemary (Rosmarinus officinalis L.) polyphenols on membrane phospholipid order.
Pérez-Fons L, Garzón MT, Micol V.
J Agric Food Chem. 2010 Jan 13;58(1):161-71.
Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/19924866
Antioxidant activity of essential oils of five spice plants widely used in a Mediterranean diet.
Manuel Viuda-Martos, Yolanda Ruiz Navajas, Elena Sánchez Zapata, Juana Fernández-López and José A. Pérez-Álvarez
Flavour and Fragrance Journal Volume 25, Issue 1, pages 13–19, January/February 2010
ResearchGate: https://www.researchgate.net/publication/229983398_Antioxidant_activity_of_essential_oils_of_five_spice_plants_widely_used_in_a_Mediterranean_diet
Chemical constituents and antioxidant properties of Rosmarinus officinalis L. essential oil cultivated from South-Western Tunisia.
Adel Kadri, Zied Zarai, Ines Ben Chobba, Ahmed Békir, Néji Gharsallah, Mohamed Damak and Radhouane Gdoura
Journal of Medicinal Plants Research Vol. 5(25), pp. 5999-6004, 9 November, 2011
academicJournals: http://www.academicjournals.org/article/article1380701466_Kadri%20et%20al.pdf
Protection from cyanide-induced brain injury by the Nrf2 transcriptional activator carnosic acid.
Zhang D, Lee B, Nutter A, Song P, Dolatabadi N, Parker J, Sanz-Blasco S, Newmeyer T, Ambasudhan R, McKercher SR, Masliah E, Lipton SA.
J Neurochem. 2015 Feb 18.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/25692407
Ameliorative effects of Rosmarinus officinalis leaf extract and Vitamin C on cadmium-induced oxidative stress in Nile tilapia Oreochromis niloticus.
Al-Anazi MS, Virk P, Elobeid M, Siddiqui MI.
J Environ Biol. 2015 Nov;36(6):1401-8.
Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/26688980
Nrf2 activation ameliorates cytotoxic effects of arsenic trioxide in acute promyelocytic leukemia cells through increased glutathione levels and arsenic efflux from cells.
Nishimoto S, Suzuki T, Koike S, Yuan B, Takagi N, Ogasawara Y.
Toxicol Appl Pharmacol. 2016 Aug 15;305:161-8
Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/27317373
Carnosic Acid Protects Mitochondria of Human Neuroblastoma SH-SY5Y Cells Exposed to Paraquat Through Activation of the Nrf2/HO-1Axis.
de Oliveira MR, Peres A, Ferreira GC, Schuck PF, Gama C, Bosco SM.
Mol Neurobiol. 2016 Sep 29.
Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/27686076
Evaluation of the effectiveness of Rosmarinus officinalis (Lamiaceae) in the alleviation of carbon tetrachloride-induced acute hepatotoxicity in the rat.
Sotelo-Félix JI, Martinez-Fong D, Muriel P, Santillán RL, Castillo D, Yahuaca P
J Ethnopharmacol. 2002 Jul; 81(2):145-54.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/12065145/
Hepatoprotective effects of Hibiscus, Rosmarinus and Salvia on azathioprine-induced toxicity in rats.
Amin A, Hamza AA
Life Sci. 2005 Jun 3; 77(3):266-78.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/15878355/
Oxidative stress modulation by Rosmarinus officinalis in CCl4-induced liver cirrhosis.
Gutiérrez R, Alvarado JL, Presno M, Pérez-Veyna O, Serrano CJ, Yahuaca P
Phytother Res. 2010 Apr; 24(4):595-601.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/19827016/
In vitro hepatotoxicity and cytochrome P450 induction and inhibition characteristics of carnosic acid, a dietary supplement with antiadipogenic properties.
Dickmann LJ, VandenBrink BM, Lin YS
Drug Metab Dispos. 2012 Jul; 40(7):1263-7
Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/22531045
Antioxidant activity of rosemary (Rosmarinus officinalis L.) essential oil and its hepatoprotective potential.
Rašković A, Milanović I, Pavlović N1, Ćebović T, Vukmirović S, Mikov M
BMC Complement Altern Med. 2014 Jul 7;14:225.
PMC: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227022/
Effects of rosmarinic acid on liver and kidney antioxidant enzymes, lipid peroxidation and tissue ultrastructure in aging mice.
Zhang Y, Chen X, Yang L, Zu Y, Lu Q.
Food Funct. 2015 Mar;6(3):927-31.
Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/25635678
Protective effects of ethanolic extract of rosemary against lead-induced hepato-renal damage in rabbits.
Mohamed WA, Abd-Elhakim YM, Farouk SM.
Exp Toxicol Pathol. 2016 Sep;68(8):451-61.
Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/27449700
Investigation of antibacterial activity of rosemary essential oil against Propionibacterium acnes with atomic force microscopy.
Fu Y, Zu Y, Chen L, Efferth T, Liang H, Liu Z, Liu W
Planta Med. 2007 Oct; 73(12):1275-80.
Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/17893831
Photoprotective effect of a water-soluble extract of Rosmarinus officinalis L. against UV-induced matrix metalloproteinase-1 in human dermal fibroblasts and reconstructed skin.
Martin R, Pierrard C, Lejeune F, Hilaire P, Breton L, Bernerd F
Eur J Dermatol. 2008 Mar-Apr; 18(2):128-35.
Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/18424370
Healing potential of Rosmarinus officinalis L. on full-thickness excision cutaneous wounds in alloxan-induced-diabetic BALB/c mice.
Abu-Al-Basal MA
J Ethnopharmacol. 2010 Sep 15; 131(2):443-50.
Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/20633625/
Effects of ethanol extracts of herbal medicines on dermatitis in an atopic dermatitis mouse model.
Takano N, Inokuchi Y, Kurachi M.
Yakugaku Zasshi. 2011 Apr;131(4):581-6.
Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/21467798
Suppression of COX-2, IL-1b and TNF- α expression and leukocyte infiltration in inflamed
skin by bioactive compounds from Rosmarinus officinalis L.
Mengoni ES, Vichera G, Rigano LA, Rodriguez-Puebla ML, Galliano SR, Cafferata EE, et al.
Fitoterapia 2011; 82(3): 41421.Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/21129455
Protective effects of citrus and rosemary extracts on UV-induced damage in skin cell model and human volunteers.
Pérez-Sánchez A, Barrajón-Catalán E, Caturla N, Castillo J, Benavente-García O, Alcaraz M, Micol V.
J Photochem Photobiol B. 2014 Jul 5;136:12-8.
Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/24815058
Skin photoprotective and antiageing effects of a combination of rosemary (Rosmarinus officinalis) and grapefruit (Citrus paradisi) polyphenols.
Nobile V, Michelotti A, Cestone E, Caturla N, Castillo J, Benavente-García O, Pérez-Sánchez A, Micol V.
Food Nutr Res. 2016 Jul 1;60:31871.
PMC: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931025/pdf/FNR-60-31871.pdf
Inhibition of complement by covalent attachment of rosmarinic acid to activated C3b.
Sahu A, Rawal N, Pangburn MK
Biochem Pharmacol. 1999 Jun 15; 57(12):1439-46.
Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/10353266/
A pilot trial evaluating Meta050, a proprietary combination of reduced iso-alpha acids, rosemary extract and oleanolic acid in patients with arthritis and fibromyalgia.
Lukaczer D, Darland G, Tripp M, Liska D, Lerman RH, Schiltz B, Bland JS
Phytother Res. 2005 Oct; 19(10):864-9.
Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/16261517/
Characterization of topical antiinflammatory compounds in Rosmarinus officinalis L.
Altinier G, Sosa S, Aquino RP, Mencherini T, Della Loggia R, Tubaro A.
J Agric Food Chem. 2007 Mar 7;55(5):1718-23.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/17288440/
Evaluation of the antinociceptive effect of Rosmarinus officinalis L. using three different experimental models in rodents.
González-Trujano ME, Peña EI, Martínez AL, Moreno J, Guevara-Fefer P, Déciga-Campos M, López-Muñoz FJ.
J Ethnopharmacol. 2007 May 22;111(3):476-82.
Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/17223299
Anti-inflammatory and antinociceptive effects of Rosmarinus officinalis L. essential oil in experimental animal models.
Takaki I, Bersani-Amado LE, Vendruscolo A, Sartoretto SM, Diniz SP, Bersani-Amado CA, Cuman RK.
J Med Food. 2008 Dec;11(4):741-6.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/19053868/
Investigations into the specific effects of rosemary oil at the receptor level.
Sagorchev P, Lukanov J, Beer AM.
Phytomedicine. 2010 Jul;17(8-9):693-7.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/20034774
Effects of extract and essential oil of Rosmarinus officinalis L. on TNBS-induced colitis in rats.
Minaiyan M, Ghannadi AR, Afsharipour M, Mahzouni P.
Res Pharm Sci. 2011 Jan;6(1):13-21.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/22049274
Analgesic effects of rosemary essential oil and its interactions with codeine and
paracetamol in mice
A. Raskovic, I. Milanovic, N. Pavlovic, B. Milijasevic, M. Ubavic, M. Mikov
Eur Rev Med Pharmacol Sci 2015; 19: 165-172
European Review for Medical and Pharmacological Sciences: http://www.europeanreview.org/wp/wp-content/uploads/165-172.pdf
Effect of Rosemarinus officinalis L. on MMP-9, MCP-1 Levels, and Cell Migration in RAW 264.7 and Smooth Muscle Cells
In Gyeong Chae, Mi Hee Yu, Nam-Kyung Im, Young Tae Jung, Jinho Lee, Kyung-Soo Chun, and In-Seon Lee
J Med Food. 2012 Oct; 15(10): 879–886.
PMC: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466913/
Effects of 1.8-cineole (eucalyptol) on the spontaneous contractile activity of smooth muscles fibre
Sagorchev Plamen, Lukanov Julian, Beer André-Michael
J. Med. Plants Res. Vol.9(14), pp. 486-493, April 2015
academicJournals: http://www.academicjournals.org/journal/JMPR/article-full-text-pdf/986E67552581
Carnosol and Related Substances Modulate Chemokine and Cytokine Production in Macrophages and Chondrocytes.
Schwager J1, Richard N2, Fowler A3, Seifert N4, Raederstorff D5.
Molecules. 2016 Apr 8;21(4):465.
Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/27070563
Effects of inhaled rosemary oil on subjective feelings and activities of the nervous system.
Sayorwan W, Ruangrungsi N, Piriyapunyporn T, Hongratanaworakit T, Kotchabhakdi N, Siripornpanich V.
Sci Pharm. 2013 Apr-Jun;81(2):531-42.
Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/23833718

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The health claims relating to other nutrients or substances contained in our products that feature on our site are compliant with Regulation No. 432/2012 of the Commission of 16 May 2012 which establishes a list of authorised health claims authorised in relation to food products, other than those in reference to the reduction of the risk of disease as well as community-based development and child health (cf. website of the European Commission: http://ec.europa.eu/nuhclaims/).